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Molecular Evolution of the TET Gene Family in Mammals

Ten-eleven translocation (TET) proteins, a family of Fe(2+)- and 2-oxoglutarate-dependent dioxygenases, are involved in DNA demethylation. They also help regulate various cellular functions. Three TET paralogs have been identified (TET1, TET2, and TET3) in humans. This study focuses on the evolution...

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Detalles Bibliográficos
Autores principales: Akahori, Hiromichi, Guindon, Stéphane, Yoshizaki, Sumio, Muto, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691057/
https://www.ncbi.nlm.nih.gov/pubmed/26633372
http://dx.doi.org/10.3390/ijms161226110

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