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Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges

Embryonic stem cells (ESCs) are chiefly characterized by their ability to self-renew and to differentiate into any cell type derived from the three main germ layers. It was demonstrated that somatic cells could be reprogrammed to form induced pluripotent stem cells (iPSCs) via various strategies. Ge...

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Detalles Bibliográficos
Autores principales:	Seah, Yu Fen Samantha, EL Farran, Chadi A., Warrier, Tushar, Xu, Jian, Loh, Yuin-Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691066/ https://www.ncbi.nlm.nih.gov/pubmed/26633382 http://dx.doi.org/10.3390/ijms161226119

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