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Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma

Increasing evidence demonstrates that dysregulation of XBP1 function contributes to tumorigenesis in some cancers. However, little is known about the role of XBP1 in the progression of osteosarcoma (OS). The expression of XBP1 in OS samples was measured by quantitative RT-PCR and Western blotting as...

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Detalles Bibliográficos
Autores principales: Yang, Jielai, Cheng, Dongdong, Zhou, Shumin, Zhu, Bin, Hu, Tu, Yang, Qingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691070/
https://www.ncbi.nlm.nih.gov/pubmed/26633383
http://dx.doi.org/10.3390/ijms161226123

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