Intravenous Single-Dose Toxicity of Redaporfin-Based Photodynamic Therapy in Rodents

We assessed the tolerability and safety in rodents of a single intravenous (i.v.) dose of redaporfin, a novel photosensitizer for Photodynamic Therapy (PDT) of cancer. Two approaches were used to evaluate acute toxicity: (i) a dose escalation study in BALB/c mice to evaluate the maximum tolerated do...

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Detalles Bibliográficos
Autores principales: Rocha, Luis B., Schaberle, Fábio, Dąbrowski, Janusz M., Simões, Sérgio, Arnaut, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691106/
https://www.ncbi.nlm.nih.gov/pubmed/26670231
http://dx.doi.org/10.3390/ijms161226162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691106/
https://www.ncbi.nlm.nih.gov/pubmed/26670231
http://dx.doi.org/10.3390/ijms161226162

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