Transducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic Perspective

Transducer of ERBB2.1 (TOB1) is a tumor-suppressor protein, which functions as a negative regulator of the receptor tyrosine-kinase ERBB2. As most of the other tumor suppressor proteins, TOB1 is inactivated in many human cancers. Homozygous deletion of TOB1 in mice is reported to be responsible for...

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Detalles Bibliográficos
Autores principales: Lee, Hun Seok, Kundu, Juthika, Kim, Ryong Nam, Shin, Young Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691146/
https://www.ncbi.nlm.nih.gov/pubmed/26694352
http://dx.doi.org/10.3390/ijms161226203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691146/
https://www.ncbi.nlm.nih.gov/pubmed/26694352
http://dx.doi.org/10.3390/ijms161226203

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