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Transducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic Perspective
Transducer of ERBB2.1 (TOB1) is a tumor-suppressor protein, which functions as a negative regulator of the receptor tyrosine-kinase ERBB2. As most of the other tumor suppressor proteins, TOB1 is inactivated in many human cancers. Homozygous deletion of TOB1 in mice is reported to be responsible for...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691146/ https://www.ncbi.nlm.nih.gov/pubmed/26694352 http://dx.doi.org/10.3390/ijms161226203 |