Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130

Starvation-induced autophagy requires activation of the ULK complex at the phagophore. Two Golgi proteins, WAC and GM130, regulate autophagy, however their mechanism of regulation is unknown. In search of novel interaction partners of WAC, we found that GM130 directly interacts with WAC, and this in...

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Detalles Bibliográficos
Autores principales: Joachim, Justin, Jefferies, Harold B.J., Razi, Minoo, Frith, David, Snijders, Ambrosius P., Chakravarty, Probir, Judith, Delphine, Tooze, Sharon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691241/
https://www.ncbi.nlm.nih.gov/pubmed/26687599
http://dx.doi.org/10.1016/j.molcel.2015.11.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691241/
https://www.ncbi.nlm.nih.gov/pubmed/26687599
http://dx.doi.org/10.1016/j.molcel.2015.11.018

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