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Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

The essential functions of the conserved Smc5/6 complex remain elusive. To uncover its roles in genome maintenance, we established Saccharomyces cerevisiae cell-cycle-regulated alleles that enable restriction of Smc5/6 components to S or G2/M. Unexpectedly, the essential functions of Smc5/6 segregat...

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Detalles Bibliográficos
Autores principales:	Menolfi, Demis, Delamarre, Axel, Lengronne, Armelle, Pasero, Philippe, Branzei, Dana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691243/ https://www.ncbi.nlm.nih.gov/pubmed/26698660 http://dx.doi.org/10.1016/j.molcel.2015.10.023

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