LymPHOS 2.0: an update of a phosphosite database of primary human T cells

LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold...

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Detalles Bibliográficos
Autores principales: Nguyen, Tien Dung, Vidal-Cortes, Oriol, Gallardo, Oscar, Abian, Joaquin, Carrascal, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Database Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691341/
https://www.ncbi.nlm.nih.gov/pubmed/26708986
http://dx.doi.org/10.1093/database/bav115
Descripción
Sumario:LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pathway. Sequence data quality has also been improved with the use of multiple search engines for database searching. LymPHOS can be publicly accessed at http://www.lymphos.org. Database URL: http://www.lymphos.org.

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