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24-Week Exposure to Oxidized Tyrosine Induces Hepatic Fibrosis Involving Activation of the MAPK/TGF-β1 Signaling Pathway in Sprague-Dawley Rats Model

Scope. Oxidized tyrosine (O-Tyr) has been widely detected in many consumer protein products. O-Tyr products such as dityrosine (Dityr) and 3-nitrotyrosine (3-NT) are universal biomarkers of protein oxidation and have been demonstrated to be associated with metabolic disorders in biological system. E...

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Detalles Bibliográficos
Autores principales: Li, Zhuqing Leslie, Shi, Yonghui, Le, Guowei, Ding, Yinyi, Zhao, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691618/
https://www.ncbi.nlm.nih.gov/pubmed/26788244
http://dx.doi.org/10.1155/2016/3123294