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Potential Modulation of Sirtuins by Oxidative Stress
Sirtuins are a conserved family of NAD-dependent protein deacylases. Initially proposed as histone deacetylases, it is now known that they act on a variety of proteins including transcription factors and metabolic enzymes, having a key role in the regulation of cellular homeostasis. Seven isoforms a...
Autores principales: | Santos, Leonardo, Escande, Carlos, Denicola, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691645/ https://www.ncbi.nlm.nih.gov/pubmed/26788256 http://dx.doi.org/10.1155/2016/9831825 |
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