RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

Forward genetic screens using Sleeping Beauty (SB)-mobilized T2/Onc transposons have been used to identify common insertion sites (CISs) associated with tumor formation. Recurrent sites of transposon insertion are commonly identified using ligation-mediated PCR (LM-PCR). Here, we use RNA sequencing...

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Detalles Bibliográficos
Autores principales: Temiz, Nuri A., Moriarity, Branden S., Wolf, Natalie K., Riordan, Jesse D., Dupuy, Adam J., Largaespada, David A., Sarver, Aaron L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691744/
https://www.ncbi.nlm.nih.gov/pubmed/26553456
http://dx.doi.org/10.1101/gr.188649.114

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