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Dynamic changes in histone modifications precede de novo DNA methylation in oocytes

Erasure and subsequent reinstatement of DNA methylation in the germline, especially at imprinted CpG islands (CGIs), is crucial to embryogenesis in mammals. The mechanisms underlying DNA methylation establishment remain poorly understood, but a number of post-translational modifications of histones...

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Detalles Bibliográficos
Autores principales:	Stewart, Kathleen R., Veselovska, Lenka, Kim, Jeesun, Huang, Jiahao, Saadeh, Heba, Tomizawa, Shin-ichi, Smallwood, Sébastien A., Chen, Taiping, Kelsey, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691949/ https://www.ncbi.nlm.nih.gov/pubmed/26584620 http://dx.doi.org/10.1101/gad.271353.115

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