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FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1

Fibroblast growth factors (FGFs) are required to specify hepatic fate within the definitive endoderm through activation of the FGF receptors (FGFRs). While the signaling pathways involved in hepatic specification are well understood, the mechanisms through which FGFs induce hepatic character within...

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Detalles Bibliográficos
Autores principales:	Twaroski, Kirk, Mallanna, Sunil K., Jing, Ran, DiFurio, Francesca, Urick, Amanda, Duncan, Stephen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691950/ https://www.ncbi.nlm.nih.gov/pubmed/26637527 http://dx.doi.org/10.1101/gad.268961.115

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