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Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting
OBJECTIVE: The aim was to assess the use of optic nerve sonography (ONS) as a quick, noninvasive diagnostic test tool for detecting raised the intracranial pressure (ICP). MATERIALS AND METHODS: A prospective blinded observational study was conducted at Obafemi Awolowo University Teaching Hospitals...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692017/ https://www.ncbi.nlm.nih.gov/pubmed/26752428 http://dx.doi.org/10.4103/0976-3147.165347 |
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author | Aduayi, Olufunso Simisola Asaleye, Christianah Mopelola Adetiloye, Victor Adebayo Komolafe, Edward Oluwole Aduayi, Victor Adovi |
author_facet | Aduayi, Olufunso Simisola Asaleye, Christianah Mopelola Adetiloye, Victor Adebayo Komolafe, Edward Oluwole Aduayi, Victor Adovi |
author_sort | Aduayi, Olufunso Simisola |
collection | PubMed |
description | OBJECTIVE: The aim was to assess the use of optic nerve sonography (ONS) as a quick, noninvasive diagnostic test tool for detecting raised the intracranial pressure (ICP). MATERIALS AND METHODS: A prospective blinded observational study was conducted at Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria. The study population consisted of 160 adult patients referred to the radiology department for cranial computed tomography (CT) scan. There were 80 subjects and 80 controls. Optic nerve sheath diameter (ONSD) was measured by a radiologist using a 7.5 Megahertz ultrasound probe while cranial CT was reviewed by other radiologists blinded to the ONSD. RESULTS: Sixty-nine subjects (86.3%) had intracranial space occupying lesions (SOL) with cranial CT confirmed features of increased ICP, mean binocular ONSD of 5.7 ± 0.59 mm while 11 (13.7%) had intracranial SOL without any cranial CT evidence of increased ICP, mean binocular ONSD of 4.8 ± 0.39 mm. The difference of mean ONSD of the two groups was statistically significant (P = 0.0001). The controls had a mean binocular ONSD of 4.5 ± 0.22 mm and the difference in mean binocular ONSD for subjects with raised ICP and the controls were also statistically significant (P = 0.0001). A cut-off value of 5.2 mm (sensitivity 81.2% [95% confidence interval (CI): 69.9–89.6], specificity 100% [95% CI: 71.5–100]) was obtained from the receiver operator characteristics curve as the mean binocular ONSD that best predicts raised ICP confirmed by at least a sign on cranial CT. CONCLUSIONS: Optic nerve sonography can differentiate between normal and elevated ICP and may serve as a useful screening tool in resource-limited practice. |
format | Online Article Text |
id | pubmed-4692017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46920172016-01-08 Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting Aduayi, Olufunso Simisola Asaleye, Christianah Mopelola Adetiloye, Victor Adebayo Komolafe, Edward Oluwole Aduayi, Victor Adovi J Neurosci Rural Pract Original Article OBJECTIVE: The aim was to assess the use of optic nerve sonography (ONS) as a quick, noninvasive diagnostic test tool for detecting raised the intracranial pressure (ICP). MATERIALS AND METHODS: A prospective blinded observational study was conducted at Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria. The study population consisted of 160 adult patients referred to the radiology department for cranial computed tomography (CT) scan. There were 80 subjects and 80 controls. Optic nerve sheath diameter (ONSD) was measured by a radiologist using a 7.5 Megahertz ultrasound probe while cranial CT was reviewed by other radiologists blinded to the ONSD. RESULTS: Sixty-nine subjects (86.3%) had intracranial space occupying lesions (SOL) with cranial CT confirmed features of increased ICP, mean binocular ONSD of 5.7 ± 0.59 mm while 11 (13.7%) had intracranial SOL without any cranial CT evidence of increased ICP, mean binocular ONSD of 4.8 ± 0.39 mm. The difference of mean ONSD of the two groups was statistically significant (P = 0.0001). The controls had a mean binocular ONSD of 4.5 ± 0.22 mm and the difference in mean binocular ONSD for subjects with raised ICP and the controls were also statistically significant (P = 0.0001). A cut-off value of 5.2 mm (sensitivity 81.2% [95% confidence interval (CI): 69.9–89.6], specificity 100% [95% CI: 71.5–100]) was obtained from the receiver operator characteristics curve as the mean binocular ONSD that best predicts raised ICP confirmed by at least a sign on cranial CT. CONCLUSIONS: Optic nerve sonography can differentiate between normal and elevated ICP and may serve as a useful screening tool in resource-limited practice. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4692017/ /pubmed/26752428 http://dx.doi.org/10.4103/0976-3147.165347 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Aduayi, Olufunso Simisola Asaleye, Christianah Mopelola Adetiloye, Victor Adebayo Komolafe, Edward Oluwole Aduayi, Victor Adovi Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title | Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title_full | Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title_fullStr | Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title_full_unstemmed | Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title_short | Optic nerve sonography: A noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
title_sort | optic nerve sonography: a noninvasive means of detecting raised intracranial pressure in a resource-limited setting |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692017/ https://www.ncbi.nlm.nih.gov/pubmed/26752428 http://dx.doi.org/10.4103/0976-3147.165347 |
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