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Dual Action of Zn(2+) on the Transport Cycle of the Dopamine Transporter

The dopamine transporter shapes dopaminergic neurotransmission by clearing extracellular dopamine and by replenishing vesicular stores. The dopamine transporter carries an endogenous binding site for Zn(2+), but the nature of the Zn(2+)-dependent modulation has remained elusive: both, inhibition and...

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Detalles Bibliográficos
Autores principales:	Li, Yang, Hasenhuetl, Peter S., Schicker, Klaus, Sitte, Harald H., Freissmuth, Michael, Sandtner, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692231/ https://www.ncbi.nlm.nih.gov/pubmed/26504078 http://dx.doi.org/10.1074/jbc.M115.688275

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