Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin

The secretion of IL-1β is a central event in the initiation of inflammation. Unlike most other cytokines, the secretion of IL-1β requires two signals: one signal to induce the intracellular up-regulation of pro-IL-1β and a second signal to drive secretion of the bioactive molecule. The release of pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ainscough, Joseph S., Gerberick, G. Frank, Kimber, Ian, Dearman, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692238/
https://www.ncbi.nlm.nih.gov/pubmed/26559977
http://dx.doi.org/10.1074/jbc.M115.680694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692238/
https://www.ncbi.nlm.nih.gov/pubmed/26559977
http://dx.doi.org/10.1074/jbc.M115.680694

Ejemplares similares