Cargando…
Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin
The secretion of IL-1β is a central event in the initiation of inflammation. Unlike most other cytokines, the secretion of IL-1β requires two signals: one signal to induce the intracellular up-regulation of pro-IL-1β and a second signal to drive secretion of the bioactive molecule. The release of pr...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692238/ https://www.ncbi.nlm.nih.gov/pubmed/26559977 http://dx.doi.org/10.1074/jbc.M115.680694 |