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Novel UDP-GalNAc Derivative Structures Provide Insight into the Donor Specificity of Human Blood Group Glycosyltransferase

Two closely related glycosyltransferases are responsible for the final step of the biosynthesis of ABO(H) human blood group A and B antigens. The two enzymes differ by only four amino acid residues, which determine whether the enzymes transfer GalNAc from UDP-GalNAc or Gal from UDP-Gal to the H-anti...

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Detalles Bibliográficos
Autores principales:	Wagner, Gerd K., Pesnot, Thomas, Palcic, Monica M., Jørgensen, Rene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692239/ https://www.ncbi.nlm.nih.gov/pubmed/26527682 http://dx.doi.org/10.1074/jbc.M115.681262

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