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Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy

Autoimmune destruction of the pancreatic islets in Type 1 diabetes is mediated by both increased proinflammatory (Teff) and decreased regulatory (Treg) T lymphocytes resulting in a significant decrease in the Treg:Teff ratio. The non-obese diabetic (NOD) mouse is an excellent in vivo model for testi...

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Detalles Bibliográficos
Autores principales:	Wang, Duncheng, Shanina, Iryna, Toyofuku, Wendy M., Horwitz, Marc S., Scott, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692265/ https://www.ncbi.nlm.nih.gov/pubmed/26674203 http://dx.doi.org/10.1371/journal.pone.0145179

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