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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Opioid-induced hyperalgesia and tolerance severely impact the clinical efficacy of opiates as pain relievers in animals and humans. The molecular mechanisms underlying both phenomena are not well understood and their elucidation should benefit from the study of animal models and from the design of a...

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Detalles Bibliográficos
Autores principales: Elhabazi, Khadija, Ayachi, Safia, Ilien, Brigitte, Simonin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692352/
https://www.ncbi.nlm.nih.gov/pubmed/25145878
http://dx.doi.org/10.3791/51264

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