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Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency

De novo mutations arise mostly in the male germline and may contribute to adverse health outcomes in subsequent generations. Traditional methods for assessing the induction of germ cell mutations require the use of large numbers of animals, making them impractical. As such, germ cell mutagenicity is...

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Detalles Bibliográficos
Autores principales:	O'Brien, Jason M., Beal, Marc A., Gingerich, John D., Soper, Lynda, Douglas, George R., Yauk, Carole L., Marchetti, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692354/ https://www.ncbi.nlm.nih.gov/pubmed/25145276 http://dx.doi.org/10.3791/51576

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