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Immuno-Stimulatory Activity of Escherichia coli Mutants Producing Kdo(2)-Monophosphoryl-Lipid A or Kdo(2)-Pentaacyl-Monophosphoryl-Lipid A
Lipid A is the active center of lipopolysaccharide which also known as endotoxin. Monophosphoryl-lipid A (MPLA) has less toxicity but retains potent immunoadjuvant activity; therefore, it can be developed as adjuvant for improving the strength and duration of the immune response to antigens. However...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692390/ https://www.ncbi.nlm.nih.gov/pubmed/26710252 http://dx.doi.org/10.1371/journal.pone.0144714 |