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Substrate Stiffness Regulates Proinflammatory Mediator Production through TLR4 Activity in Macrophages
Clinical data show that disease adversely affects tissue elasticity or stiffness. While macrophage activity plays a critical role in driving disease pathology, there are limited data available on the effects of tissue stiffness on macrophage activity. In this study, the effects of substrate stiffnes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692401/ https://www.ncbi.nlm.nih.gov/pubmed/26710072 http://dx.doi.org/10.1371/journal.pone.0145813 |