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Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway

Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival. The objective of this study was to determine the impact of obesity on breast cancer cell ERβ expression, which is...

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Detalles Bibliográficos
Autores principales: Bowers, Laura W., Wiese, Megan, Brenner, Andrew J., Rossi, Emily L., Tekmal, Rajeshwar R., Hursting, Stephen D., deGraffenried, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692402/
https://www.ncbi.nlm.nih.gov/pubmed/26709918
http://dx.doi.org/10.1371/journal.pone.0145452