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Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization*

Immune responses are critically regulated by the functions of CD4 helper T cells. Based on their secreted cytokines, helper T cells are further categorized into different subsets like Treg or Th17 cells, which suppress or promote inflammatory responses, respectively. Signals from IL-2 activate the t...

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Detalles Bibliográficos
Autores principales: Hsiao, Wan-Yi, Lin, Yu-Chun, Liao, Fang-Hsuean, Chan, Yi-Chiao, Huang, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692422/
https://www.ncbi.nlm.nih.gov/pubmed/26710253
http://dx.doi.org/10.1371/journal.pone.0145880