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Modeling the Slow CD4+ T Cell Decline in HIV-Infected Individuals

The progressive loss of CD4+ T cell population is the hallmark of HIV-1 infection but the mechanism underlying the slow T cell decline remains unclear. Some recent studies suggested that pyroptosis, a form of programmed cell death triggered during abortive HIV infection, is associated with the relea...

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Detalles Bibliográficos
Autores principales: Wang, Sunpeng, Hottz, Patricia, Schechter, Mauro, Rong, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692447/
https://www.ncbi.nlm.nih.gov/pubmed/26709961
http://dx.doi.org/10.1371/journal.pcbi.1004665