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Modulation of Cytokine Secretion Allows CD4 T Cells Secreting IL-10 and IL-17 to Simultaneously Participate in Maintaining Tolerance and Immunity

CD4 T cells secreting IL-10 or IL-17 are frequent at mucosal sites, where their equilibrium is important for simultaneously maintaining tolerance and immunity to the resident microbiota. The mode of action of these cells, however, is as yet incompletely understood. In this study, we have combined ex...

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Detalles Bibliográficos
Autores principales: Saito, Kanako, Pignon, Pascale, Ayyoub, Maha, Valmori, Danila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692480/
https://www.ncbi.nlm.nih.gov/pubmed/26709703
http://dx.doi.org/10.1371/journal.pone.0145788