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Gating the glutamate gate of CLC-2 chloride channel by pore occupancy
CLC-2 channels are dimeric double-barreled chloride channels that open in response to hyperpolarization. Hyperpolarization activates protopore gates that independently regulate the permeability of the pore in each subunit and the common gate that affects the permeability through both pores. CLC-2 ch...
Autores principales: | De Jesús-Pérez, José J., Castro-Chong, Alejandra, Shieh, Ru-Chi, Hernández-Carballo, Carmen Y., De Santiago-Castillo, José A., Arreola, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692487/ https://www.ncbi.nlm.nih.gov/pubmed/26666914 http://dx.doi.org/10.1085/jgp.201511424 |
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