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The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
Multiple endocrine neoplasia type 1 (MEN1) is a genetic disorder characterized by tissue-specific tumors in the endocrine pancreas, parathyroid, and pituitary glands. Although tumor development in these tissues is dependent upon genetic inactivation of the tumor suppressor Men1, loss of both alleles...
Autores principales: | McKimpson, Wendy M., Yuan, Ziqiang, Zheng, Min, Crabtree, Judy S., Libutti, Steven K., Kitsis, Richard N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692498/ https://www.ncbi.nlm.nih.gov/pubmed/26709830 http://dx.doi.org/10.1371/journal.pone.0145792 |
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