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Human Gut-Commensalic Lactobacillus ruminis ATCC 25644 Displays Sortase-Assembled Surface Piliation: Phenotypic Characterization of Its Fimbrial Operon through In Silico Predictive Analysis and Recombinant Expression in Lactococcus lactis
Sortase-dependent surface pili (or fimbriae) in Gram-positive bacteria are well documented as a key virulence factor for certain harmful opportunistic pathogens. However, it is only recently known that these multi-subunit protein appendages are also belonging to the “friendly” commensals and now, wi...
Autores principales: | Yu, Xia, Jaatinen, Annukka, Rintahaka, Johanna, Hynönen, Ulla, Lyytinen, Outi, Kant, Ravi, Åvall-Jääskeläinen, Silja, von Ossowski, Ingemar, Palva, Airi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692528/ https://www.ncbi.nlm.nih.gov/pubmed/26709916 http://dx.doi.org/10.1371/journal.pone.0145718 |
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