Cargando…

Differentially Expressed in Chondrocytes 2 (DEC2) Increases the Expression of IL-1β and Is Abundantly Present in Synovial Membrane in Rheumatoid Arthritis

OBJECTIVE: Patients with rheumatoid arthritis (RA) have altered circadian rhythm of circulating serum cortisol, melatonin and IL-6, as well as disturbance in the expression of clock genes ARNTL2 and NPAS2. In humans, TNFα increases the expression ARNTL2 and NPAS2 but paradoxically suppresses clock o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olkkonen, Juri, Kouri, Vesa-Petteri, Hynninen, Joel, Konttinen, Yrjö T., Mandelin, Jami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692547/ https://www.ncbi.nlm.nih.gov/pubmed/26710124 http://dx.doi.org/10.1371/journal.pone.0145279

Ejemplares similares

DEC2 Blocks the Effect of the ARNTL2/NPAS2 Dimer on the Expression of PER3 and DBP
por: Olkkonen, Juri, et al.
Publicado: (2017)

Circadian Timekeeping Is Disturbed in Rheumatoid Arthritis at Molecular Level
por: Kouri, Vesa-Petteri, et al.
Publicado: (2013)

IL-17A and TNF synergistically drive expression of proinflammatory mediators in synovial fibroblasts via IκBζ-dependent induction of ELF3
por: Kouri, Vesa-Petteri, et al.
Publicado: (2022)

DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features
por: Paloneva, Juha, et al.
Publicado: (2003)

Identification of histamine receptor subtypes in skeletal myogenesis
por: CHEN, YAN, et al.
Publicado: (2015)

ICAM-1 expression on chondrocytes in rheumatoid arthritis: induction by synovial cytokines
por: Davies, M. E., et al.
Publicado: (1992)

Fibroblast biology: Signals targeting the synovial fibroblast in arthritis
por: Konttinen, Yrjö T, et al.
Publicado: (2000)

The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation
por: Wang, Xingzhi, et al.
Publicado: (2021)

Differentiated embryonic chondrocyte expressed gene-1 (DEC1) enhances the development of colorectal cancer with an involvement of the STAT3 signaling
por: Shan, Enfang, et al.
Publicado: (2022)

Expression levels of IL-15 and IL-17 in synovial fluid of rheumatoid arthritis animal model
por: Jin, Yi, et al.
Publicado: (2018)

Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion
por: Ma, Guo-Feng, et al.
Publicado: (2009)

Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
por: Ernestam, Sofia, et al.
Publicado: (2006)

Synovial lymphoid neogenesis is associated with IL-23 expression and disease activity in rheumatoid arthritis
por: Cañete, Juan D, et al.
Publicado: (2011)

The synovial microenvironment suppresses chondrocyte hypertrophy and promotes articular chondrocyte differentiation
por: Chau, Michael, et al.
Publicado: (2022)

Toll-like receptors in human chondrocytes and osteoarthritic cartilage
por: Sillat, Tarvo, et al.
Publicado: (2013)

The Cost-Effectiveness of Biologics for the Treatment of Rheumatoid Arthritis: A Systematic Review
por: Joensuu, Jaana T., et al.
Publicado: (2015)

Increased n-6 Polyunsaturated Fatty Acids Indicate Pro- and Anti-Inflammatory Lipid Modifications in Synovial Membranes with Rheumatoid Arthritis
por: Mustonen, Anne-Mari, et al.
Publicado: (2023)

Differential gene expression of proliferating synovial fibroblasts in rheumatoid arthritis
por: Masuda, KM, et al.
Publicado: (2002)

DEC1 and DEC2 Crosstalk between Circadian Rhythm and Tumor Progression
por: Sato, Fuyuki, et al.
Publicado: (2016)

Expression of TRAIL-R2 (DR5) on fibroblasts from synovial fluid of rheumatoid arthritis
por: Miranda, E, et al.
Publicado: (2004)

CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN
por: Ono, Daisuke, et al.
Publicado: (2021)

Effects of β2 Integrins on Osteoclasts, Macrophages, Chondrocytes, and Synovial Fibroblasts in Osteoarthritis
por: Hu, Tiantian, et al.
Publicado: (2022)

DEC2 expression is positively correlated with HIF-1 activation and the invasiveness of human osteosarcomas
por: Hu, Tu, et al.
Publicado: (2015)

High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis
por: Magnusson, Sofia E, et al.
Publicado: (2007)

Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients
por: Chapuy-Regaud, S, et al.
Publicado: (2003)

Intracellular expression of CXCR3 on rheumatoid arthritis synovial tissue cells
por: Krystufkova, O, et al.
Publicado: (2001)

Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
por: Narasimhan, Rekha, et al.
Publicado: (2018)

Basement membrane collagen type IV expression by human mesenchymal stem cells during adipogenic differentiation
por: Sillat, Tarvo, et al.
Publicado: (2012)

Expression of the EGF-TM7 family members EMR-2 and CD97 in rheumatoid synovial tissue
por: Kop, EN, et al.
Publicado: (2002)

Prostaglandin E(2 )is an enhancer for IL-1β-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts
por: Kojima, F, et al.
Publicado: (2003)

Immune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases
por: Takakubo, Yuya, et al.
Publicado: (2012)

Rheumatoid arthritis is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes
por: Caetano-Lopes, Joana, et al.
Publicado: (2011)

Anti-aging effects of Korean Red Ginseng (KRG) in differentiated embryo chondrocyte (DEC) knockout mice
por: Nam, Youn Hee, et al.
Publicado: (2021)

Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE(2) pathway
por: Peng, Anping, et al.
Publicado: (2019)

E2F2 stimulates CCR4 expression and activates synovial fibroblast-like cells in rheumatoid arthritis
por: Xu, Wanju, et al.
Publicado: (2021)

Systematic Review and Meta-Analysis of the Efficacy and Safety of Existing TNF Blocking Agents in Treatment of Rheumatoid Arthritis
por: Aaltonen, Kalle J., et al.
Publicado: (2012)

The Role of COX-2 in Rheumatoid Arthritis Synovial Tissues
por: Crofford, Leslie J
Publicado: (2000)

DEC2 expression antagonizes cisplatin-induced apoptosis in human esophageal squamous cell carcinoma
por: Sato, Hidenobu, et al.
Publicado: (2017)

Effect of Zoledronate on the Expression of Vascular Endothelial Growth Factor-A by Articular Chondrocytes and Synovial Cells: An in Vitro Study
por: Yi, Jin Woong, et al.
Publicado: (2014)

Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues
por: Shahrara, Shiva, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_1j2dms668apcs238dilcmlpbq0