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Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke

BACKGROUND: Stroke is the third most common death reason after the cardiovascular disorders and cancer. Cerebral ischemia is a pathology that stems from a decrease in cerebral perfusion. Computed Tomography Perfusion (CTP) is an additional method to the conventional Computed Tomography (CT) that cou...

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Autores principales: Menzilcioglu, Mehmet Sait, Mete, Ahmet, Ünverdi, Zeyni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692568/
https://www.ncbi.nlm.nih.gov/pubmed/26740827
http://dx.doi.org/10.12659/PJR.895468
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author Menzilcioglu, Mehmet Sait
Mete, Ahmet
Ünverdi, Zeyni
author_facet Menzilcioglu, Mehmet Sait
Mete, Ahmet
Ünverdi, Zeyni
author_sort Menzilcioglu, Mehmet Sait
collection PubMed
description BACKGROUND: Stroke is the third most common death reason after the cardiovascular disorders and cancer. Cerebral ischemia is a pathology that stems from a decrease in cerebral perfusion. Computed Tomography Perfusion (CTP) is an additional method to the conventional Computed Tomography (CT) that could be performed by using developed softwares, in a short period of time and with a low risk of complications. CTP not only allows early detection of cerebral ischemia but also gives valuable information on the ischemic penumbra which are very important in early diagnosis and treatment. Acute Ischemic Stroke (AIS) can be cured by trombolytic treapy within 3–6 hours after symptom onset. Since rapid screening and accurate diagnosis increase the success of the treatment, the role of neuroradiology in acute ischemia diagnostics and treatment has become more important. Our aim was to define CT skills in early diagnosis of AIS, to define its contribution to patient’s diagnosis and treatment and to define its importance regarding patient’s prognosis. MATERIAL/METHODS: We included 42 patients that presented to the emergency service and neurology outpatient clinic with the symptoms of acute cerebral incidence. RESULTS: In our study, we found that Cerebral Blood Flow (CBF) is 90.91% sensitive and 100% specific in examining ischemia. CONCLUSIONS: Tissue hemodynamic data, especially sensitivity and specificity rates, which cannot be acquired by conventional CT and MRI methods, can be acquired by the CTP method.
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spelling pubmed-46925682016-01-06 Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke Menzilcioglu, Mehmet Sait Mete, Ahmet Ünverdi, Zeyni Pol J Radiol Original Article BACKGROUND: Stroke is the third most common death reason after the cardiovascular disorders and cancer. Cerebral ischemia is a pathology that stems from a decrease in cerebral perfusion. Computed Tomography Perfusion (CTP) is an additional method to the conventional Computed Tomography (CT) that could be performed by using developed softwares, in a short period of time and with a low risk of complications. CTP not only allows early detection of cerebral ischemia but also gives valuable information on the ischemic penumbra which are very important in early diagnosis and treatment. Acute Ischemic Stroke (AIS) can be cured by trombolytic treapy within 3–6 hours after symptom onset. Since rapid screening and accurate diagnosis increase the success of the treatment, the role of neuroradiology in acute ischemia diagnostics and treatment has become more important. Our aim was to define CT skills in early diagnosis of AIS, to define its contribution to patient’s diagnosis and treatment and to define its importance regarding patient’s prognosis. MATERIAL/METHODS: We included 42 patients that presented to the emergency service and neurology outpatient clinic with the symptoms of acute cerebral incidence. RESULTS: In our study, we found that Cerebral Blood Flow (CBF) is 90.91% sensitive and 100% specific in examining ischemia. CONCLUSIONS: Tissue hemodynamic data, especially sensitivity and specificity rates, which cannot be acquired by conventional CT and MRI methods, can be acquired by the CTP method. International Scientific Literature, Inc. 2015-12-21 /pmc/articles/PMC4692568/ /pubmed/26740827 http://dx.doi.org/10.12659/PJR.895468 Text en © Pol J Radiol, 2015 This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Original Article
Menzilcioglu, Mehmet Sait
Mete, Ahmet
Ünverdi, Zeyni
Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title_full Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title_fullStr Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title_full_unstemmed Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title_short Effectiveness of CT Computed Tomography Perfusion in Diagnostics of Acute Ischemic Stroke
title_sort effectiveness of ct computed tomography perfusion in diagnostics of acute ischemic stroke
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692568/
https://www.ncbi.nlm.nih.gov/pubmed/26740827
http://dx.doi.org/10.12659/PJR.895468
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