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Down-Regulation of miR-148a Promotes Metastasis by DNA Methylation and is Associated with Prognosis of Skin Cancer by Targeting TGIF2

BACKGROUND: MicroRNAs (miRNA) dysregulation has been considered to be significantly related to the occurrence and development of cancers. Several studies had proved that DNA methylation is an important cause of the abnormal expression of miRNAs. The purpose of this study was to investigate the methy...

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Detalles Bibliográficos
Autores principales: Tian, Yanli, Wei, Wei, Li, Li, Yang, Rongya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692572/
https://www.ncbi.nlm.nih.gov/pubmed/26638007
http://dx.doi.org/10.12659/MSM.894826