A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

Objective. Glyoxalase-1 is an enzyme detoxifying methylglyoxal (MG). MG is a potent precursor of advanced glycation endproducts which are regarded to be a key player in micro- and macrovascular damage. Yet, the role of Glo1 in atherosclerosis remains unclear. In this study, the effect of Glo1 on mou...

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Detalles Bibliográficos
Autores principales: Wortmann, Markus, Hakimi, Maani, Fleming, Thomas, Peters, Andreas S., Sijmonsma, Tjeerd P., Herzig, Stephan, Nawroth, Peter P., Böckler, Dittmar, Dihlmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693023/
https://www.ncbi.nlm.nih.gov/pubmed/26788517
http://dx.doi.org/10.1155/2016/2981639

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