Full Genomic Characterization of a Saffold Virus Isolated in Peru

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold...

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Autores principales: Leguia, Mariana, Loyola, Steev, Rios, Jane, Juarez, Diana, Guevara, Carolina, Silva, Maria, Prieto, Karla, Wiley, Michael, Kasper, Matthew R., Palacios, Gustavo, Bausch, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693166/
https://www.ncbi.nlm.nih.gov/pubmed/26610576
http://dx.doi.org/10.3390/pathogens4040816
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author Leguia, Mariana
Loyola, Steev
Rios, Jane
Juarez, Diana
Guevara, Carolina
Silva, Maria
Prieto, Karla
Wiley, Michael
Kasper, Matthew R.
Palacios, Gustavo
Bausch, Daniel G.
author_facet Leguia, Mariana
Loyola, Steev
Rios, Jane
Juarez, Diana
Guevara, Carolina
Silva, Maria
Prieto, Karla
Wiley, Michael
Kasper, Matthew R.
Palacios, Gustavo
Bausch, Daniel G.
author_sort Leguia, Mariana
collection PubMed
description While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.
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spelling pubmed-46931662016-01-06 Full Genomic Characterization of a Saffold Virus Isolated in Peru Leguia, Mariana Loyola, Steev Rios, Jane Juarez, Diana Guevara, Carolina Silva, Maria Prieto, Karla Wiley, Michael Kasper, Matthew R. Palacios, Gustavo Bausch, Daniel G. Pathogens Short Communication While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas. MDPI 2015-11-20 /pmc/articles/PMC4693166/ /pubmed/26610576 http://dx.doi.org/10.3390/pathogens4040816 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Communication
Leguia, Mariana
Loyola, Steev
Rios, Jane
Juarez, Diana
Guevara, Carolina
Silva, Maria
Prieto, Karla
Wiley, Michael
Kasper, Matthew R.
Palacios, Gustavo
Bausch, Daniel G.
Full Genomic Characterization of a Saffold Virus Isolated in Peru
title Full Genomic Characterization of a Saffold Virus Isolated in Peru
title_full Full Genomic Characterization of a Saffold Virus Isolated in Peru
title_fullStr Full Genomic Characterization of a Saffold Virus Isolated in Peru
title_full_unstemmed Full Genomic Characterization of a Saffold Virus Isolated in Peru
title_short Full Genomic Characterization of a Saffold Virus Isolated in Peru
title_sort full genomic characterization of a saffold virus isolated in peru
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693166/
https://www.ncbi.nlm.nih.gov/pubmed/26610576
http://dx.doi.org/10.3390/pathogens4040816
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