A Nanoparticle Based Sp17 Peptide Vaccine Exposes New Immuno-Dominant and Species Cross-reactive B Cell Epitopes

Sperm protein antigen 17 (Sp17), expressed in primary as well as in metastatic lesions in >83% of patients with ovarian cancer, is a promising ovarian cancer vaccine candidate. Herein we describe the formulation of nanoparticle based vaccines based on human Sp17 (hSp17) sequence derived peptides,...

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Detalles Bibliográficos
Autores principales: Xiang, Sue D., Gao, Qian, Wilson, Kirsty L., Heyerick, Arne, Plebanski, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693223/
https://www.ncbi.nlm.nih.gov/pubmed/26529027
http://dx.doi.org/10.3390/vaccines3040875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693223/
https://www.ncbi.nlm.nih.gov/pubmed/26529027
http://dx.doi.org/10.3390/vaccines3040875

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