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Modulation of Intestinal Barrier and Bacterial Endotoxin Production Contributes to the Beneficial Effect of Nicotinic Acid on Alcohol-Induced Endotoxemia and Hepatic Inflammation in Rats

Alcohol consumption causes nicotinic acid deficiency. The present study was undertaken to determine whether dietary nicotinic acid supplementation provides beneficial effects on alcohol-induced endotoxin signaling and the possible mechanisms at the gut-liver axis. Male Sprague-Dawley rats were pair-...

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Detalles Bibliográficos
Autores principales: Zhong, Wei, Li, Qiong, Zhang, Wenliang, Sun, Qian, Sun, Xinguo, Zhou, Zhanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693251/
https://www.ncbi.nlm.nih.gov/pubmed/26501337
http://dx.doi.org/10.3390/biom5042643

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