HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA

Unspliced, genomic HIV-1 RNA (vRNA) is a component of several ribonucleoprotein complexes (RNP) during the viral replication cycle. In earlier work, we demonstrated that the host upframeshift protein 1 (UPF1), a key factor in nonsense-mediated mRNA decay (NMD), colocalized and associated to the vira...

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Detalles Bibliográficos
Autores principales: Ajamian, Lara, Abel, Karen, Rao, Shringar, Vyboh, Kishanda, García-de-Gracia, Francisco, Soto-Rifo, Ricardo, Kulozik, Andreas E., Gehring, Niels H., Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693258/
https://www.ncbi.nlm.nih.gov/pubmed/26492277
http://dx.doi.org/10.3390/biom5042808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693258/
https://www.ncbi.nlm.nih.gov/pubmed/26492277
http://dx.doi.org/10.3390/biom5042808

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