Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer

Generation of a stable, soluble mimic of the HIV-1 envelope glycoprotein (Env) trimer on the virion surface has been considered an important first step for developing a successful HIV-1 vaccine. Recently, a soluble native-like Env trimer (BG505 SOSIP.664) has been described. This protein has facilit...

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Detalles Bibliográficos
Autores principales: Sliepen, Kwinten, van Montfort, Thijs, Ozorowski, Gabriel, Pritchard, Laura K., Crispin, Max, Ward, Andrew B., Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693263/
https://www.ncbi.nlm.nih.gov/pubmed/26512709
http://dx.doi.org/10.3390/biom5042919

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