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In Vivo Acute on Chronic Ethanol Effects in Liver: A Mouse Model Exhibiting Exacerbated Injury, Altered Metabolic and Epigenetic Responses

Chronic alcoholics who also binge drink (i.e., acute on chronic) are prone to an exacerbated liver injury but its mechanism is not understood. We therefore investigated the in vivo effects of chronic and binge ethanol ingestion and compared to chronic ethanol followed by three repeat binge ethanol o...

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Detalles Bibliográficos
Autores principales: Shukla, Shivendra D., Aroor, Annayya R., Restrepo, Ricardo, Kharbanda, Kusum K., Ibdah, Jamal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693278/
https://www.ncbi.nlm.nih.gov/pubmed/26610587
http://dx.doi.org/10.3390/biom5043280