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In Vivo Acute on Chronic Ethanol Effects in Liver: A Mouse Model Exhibiting Exacerbated Injury, Altered Metabolic and Epigenetic Responses
Chronic alcoholics who also binge drink (i.e., acute on chronic) are prone to an exacerbated liver injury but its mechanism is not understood. We therefore investigated the in vivo effects of chronic and binge ethanol ingestion and compared to chronic ethanol followed by three repeat binge ethanol o...
Autores principales: | Shukla, Shivendra D., Aroor, Annayya R., Restrepo, Ricardo, Kharbanda, Kusum K., Ibdah, Jamal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693278/ https://www.ncbi.nlm.nih.gov/pubmed/26610587 http://dx.doi.org/10.3390/biom5043280 |
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