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A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response

BMI1 plays critical roles in maintaining the self-renewal of hematopoietic, neural, intestinal stem cells, and cancer stem cells (CSCs) for a variety of cancer types. BMI1 promotes cell proliferative life span and epithelial to mesenchymal transition (EMT). Upregulation of BMI1 occurs in multiple ca...

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Detalles Bibliográficos
Autores principales:	Lin, Xiaozeng, Ojo, Diane, Wei, Fengxiang, Wong, Nicholas, Gu, Yan, Tang, Damu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693283/ https://www.ncbi.nlm.nih.gov/pubmed/26633535 http://dx.doi.org/10.3390/biom5043396

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