To evaluate the biocompatibility of the Indian Portland cement with potential for use in dentistry: An animal study

AIMS: This study evaluated the biocompatibility of the Indian Portland cement with potential for use in dentistry. MATERIALS AND METHODS: This study was performed in Swiss albino mice, by implanting the Indian Portland cement pellets subcutaneously. After 1, 3, and 6 weeks the tissue specimens were prepared for histological examination. RESULTS: The histological analysis showed moderate to severe inflammation at 1 week. The inflammation gradually decreased by 6 weeks, with most of the specimens showing the absence of inflammatory reaction. CONCLUSIONS: According to these experimental conditions, the tested Indian Portland cement was biocompatible.