Cargando…
Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide
Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans’ cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cuta...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693353/ https://www.ncbi.nlm.nih.gov/pubmed/26753141 http://dx.doi.org/10.4103/2229-5178.169743 |
_version_ | 1782407370206347264 |
---|---|
author | Subramaniyan, Radhakrishnan Ramachandran, Rajagopal Rajangam, Gnanasekaran Donaparthi, Navya |
author_facet | Subramaniyan, Radhakrishnan Ramachandran, Rajagopal Rajangam, Gnanasekaran Donaparthi, Navya |
author_sort | Subramaniyan, Radhakrishnan |
collection | PubMed |
description | Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans’ cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide. |
format | Online Article Text |
id | pubmed-4693353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46933532016-01-08 Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide Subramaniyan, Radhakrishnan Ramachandran, Rajagopal Rajangam, Gnanasekaran Donaparthi, Navya Indian Dermatol Online J Case Report Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans’ cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4693353/ /pubmed/26753141 http://dx.doi.org/10.4103/2229-5178.169743 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Subramaniyan, Radhakrishnan Ramachandran, Rajagopal Rajangam, Gnanasekaran Donaparthi, Navya Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title | Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title_full | Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title_fullStr | Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title_full_unstemmed | Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title_short | Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
title_sort | purely cutaneous langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693353/ https://www.ncbi.nlm.nih.gov/pubmed/26753141 http://dx.doi.org/10.4103/2229-5178.169743 |
work_keys_str_mv | AT subramaniyanradhakrishnan purelycutaneouslangerhanscellhistiocytosispresentingasanulceronthechininanelderlymansuccessfullytreatedwiththalidomide AT ramachandranrajagopal purelycutaneouslangerhanscellhistiocytosispresentingasanulceronthechininanelderlymansuccessfullytreatedwiththalidomide AT rajangamgnanasekaran purelycutaneouslangerhanscellhistiocytosispresentingasanulceronthechininanelderlymansuccessfullytreatedwiththalidomide AT donaparthinavya purelycutaneouslangerhanscellhistiocytosispresentingasanulceronthechininanelderlymansuccessfullytreatedwiththalidomide |