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Multiple nodules on the sole of the foot
Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693358/ https://www.ncbi.nlm.nih.gov/pubmed/26753144 http://dx.doi.org/10.4103/2229-5178.169720 |
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author | Miceli, Alyssa J. Junkins-Hopkins, Jacqueline M. Polley, Dennis C. Elston, Dirk M. |
author_facet | Miceli, Alyssa J. Junkins-Hopkins, Jacqueline M. Polley, Dennis C. Elston, Dirk M. |
author_sort | Miceli, Alyssa J. |
collection | PubMed |
description | Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations. |
format | Online Article Text |
id | pubmed-4693358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46933582016-01-08 Multiple nodules on the sole of the foot Miceli, Alyssa J. Junkins-Hopkins, Jacqueline M. Polley, Dennis C. Elston, Dirk M. Indian Dermatol Online J Cases from Ackerman Academy Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4693358/ /pubmed/26753144 http://dx.doi.org/10.4103/2229-5178.169720 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Cases from Ackerman Academy Miceli, Alyssa J. Junkins-Hopkins, Jacqueline M. Polley, Dennis C. Elston, Dirk M. Multiple nodules on the sole of the foot |
title | Multiple nodules on the sole of the foot |
title_full | Multiple nodules on the sole of the foot |
title_fullStr | Multiple nodules on the sole of the foot |
title_full_unstemmed | Multiple nodules on the sole of the foot |
title_short | Multiple nodules on the sole of the foot |
title_sort | multiple nodules on the sole of the foot |
topic | Cases from Ackerman Academy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693358/ https://www.ncbi.nlm.nih.gov/pubmed/26753144 http://dx.doi.org/10.4103/2229-5178.169720 |
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