Analysis of chromosome 22q11 copy number variations by multiplex ligation-dependent probe amplification for prenatal diagnosis of congenital heart defect

BACKGROUND: Congenital heart defects (CHD) represent one of the most common birth defects. This study aimed to evaluate the value of multiplex ligation-dependent probe amplification (MLPA) as a tool to detect the copy number variations (CNVs) of 22q11 in fetuses with CHD. RESULTS: A large cohort of...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Ma, Dingyuan, Wang, Yan, Cao, Li, Wu, Yun, Qiao, Fengchang, Liu, An, Li, Li, Lin, Ying, Liu, Gang, Liu, Cuiyun, Hu, Ping, Xu, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693415/
https://www.ncbi.nlm.nih.gov/pubmed/26715944
http://dx.doi.org/10.1186/s13039-015-0209-5

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