β‐Guanidinopropionic acid extends the lifespan of Drosophila melanogaster via an AMP‐activated protein kinase‐dependent increase in autophagy

Previous studies have demonstrated that AMP‐activated protein kinase (AMPK) controls autophagy through the mammalian target of rapamycin (mTOR) and Unc‐51 like kinase 1 (ULK1/Atg1) signaling, which augments the quality of cellular housekeeping, and that β‐guanidinopropionic acid (β‐GPA), a creatine...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Si, Long, Li‐Hong, Li, Di, Zhang, Jian‐Kang, Jin, Shan, Wang, Fang, Chen, Jian‐Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693457/
https://www.ncbi.nlm.nih.gov/pubmed/26120775
http://dx.doi.org/10.1111/acel.12371

Ejemplares similares

Ejemplares similares