Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

The most important physiological mechanism mediating enhanced exercise performance is increased sympathetic, beta adrenergic receptor (β‐AR), and adenylyl cyclase (AC) activity. This is the first report of decreased AC activity mediating increased exercise performance. We demonstrated that AC5 disru...

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Detalles Bibliográficos
Autores principales: Vatner, Dorothy E., Yan, Lin, Lai, Lo, Yuan, Chujun, Mouchiroud, Laurent, Pachon, Ronald E., Zhang, Jie, Dillinger, Jean‐Guillaume, Houtkooper, Riekelt H., Auwerx, Johan, Vatner, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693460/
https://www.ncbi.nlm.nih.gov/pubmed/26424149
http://dx.doi.org/10.1111/acel.12401

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