Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients

The epigenomic landscape of Parkinson's disease (PD) remains unknown. We performed a genomewide DNA methylation and a transcriptome studies in induced pluripotent stem cell (iPSC)‐derived dopaminergic neurons (DAn) generated by cell reprogramming of somatic skin cells from patients with monogen...

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Detalles Bibliográficos
Autores principales: Fernández‐Santiago, Rubén, Carballo‐Carbajal, Iria, Castellano, Giancarlo, Torrent, Roger, Richaud, Yvonne, Sánchez‐Danés, Adriana, Vilarrasa‐Blasi, Roser, Sánchez‐Pla, Alex, Mosquera, José Luis, Soriano, Jordi, López‐Barneo, José, Canals, Josep M, Alberch, Jordi, Raya, Ángel, Vila, Miquel, Consiglio, Antonella, Martín‐Subero, José I, Ezquerra, Mario, Tolosa, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693505/
https://www.ncbi.nlm.nih.gov/pubmed/26516212
http://dx.doi.org/10.15252/emmm.201505439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693505/
https://www.ncbi.nlm.nih.gov/pubmed/26516212
http://dx.doi.org/10.15252/emmm.201505439

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